This species is native to Mexico, Central and South America, from where it has spread and naturalised widely throughout tropical and subtropical regions, as well as in Australia, South Africa and southern Europe.
In the Canary Islands it is frequently cultivated as an ornamental, although it sometimes escapes from gardens and grows wild near houses, roadsides, etc. It requires little care and is very easy to grow.
Its cultivation requires little care and it is very easy to maintain. It grows best in sunny places, and can be pruned very well, and specimens can be shaped as desired, or form very dense and colourful hedges.

In some places, such as India, Australia and South Africa, it has become an invasive plant, and spreads so rapidly that efforts to eradicate it have failed completely, as it is also resistant to fire, and quickly colonises burnt areas.
Although its leaves and fruits are considered toxic, as they contain an alkaloid called lantanine, in its regions of origin the infusion of this plant is used to combat dysentery, diarrhoea, vomiting, stomach pain, liver pain and toothache.

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